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Subject: Re: EE: re: Syrian Rue
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>
> The diet thing is not an issue if you're talking about a single dose. See
> Ott's experiments with this. He ate everything you're not supposed to and
> never had a negative effect.
>
> Don't worry. Be happy.
>
> -Jeff

But at first I would be careful- depending on your blood presure it could be
dangerous, imho - most stuff listed as avoidable could be an exageration but
others... -

from deoxy site:

Q. Please review the dietary restrictions that should be observed when a
patient is receiving monoamine oxidase inhibitor (MAOI) therapy?

R. Tyramine, is an amino acid which is found in various foods, and is an
indirect sympathomimetic that can cause a hypertensive reaction in patients
receiving MAOI therapy. Monoamine oxidase is found in the gastrointestinal
tract and inactivates tyramine; when drugs prevent the catabolism of
exogenous tyramine, this amino acid is absorbed and displaces norepinephrine
from sympathetic nerve ending and epinephrine from the adrenal glands. If a
sufficient amount of pressor amines are released, a patient may experience a
severe occipital or temporal headache, diaphoresis, mydriasis, nuchal
rigidity, palpitations, and the elevation of both diastolic and systolic
blood pressure may ensue (Anon, 1989; Da Prada et al, 1988; Brown & Bryant,
1988). On rare occasions, cardiac arrhythmias, cardiac failure, and
intracerebral hemorrhage have developed in patients receiving MAOI therapy
that did not observe dietary restrictions (Brown & Bryant, 1988). Therefore,
dietary restrictions are required for patients receiving MAOIs. Extensive
dietary restrictions previously published were collected over a decade ago
and due to changes in food processing and more reliable analytical methods,
new recommendations have been published (Anon, 1989; McCabe, 1986). The
tyramine content of foods varies greatly due to the differences in
processing, fermentation, ripening, degradation, or incidental
contamination. Many foods contain small amounts of tyramine and the
formation of large quantities of tyramine have been reported if products
were aged, fermented, or left to spoil. Because the sequela from tyramine
and MAOIs is dose-related, reactions can be minimized without total
abstinence from tyramine-containing foods. Approximately 10 to 25 mg of
tyramine is required for a severe reaction compared to 6 to 10 mg for a mild
reaction. Foods that normally contain low amounts of tyramine may become a
risk if unusually large quantities are consumed or if spoilage has occurred
(McCabe, 1986). Three lists were compiled (foods to avoid, foods that may
used in small quantities, and foods with insufficient evidence to restrict)
to minimized the strict dietary restrictions that were previously used and
improve compliance and safety of MAOI therapy. The foods to avoid list
consists of foods with sufficient tyramine (in small or usual serving sizes)
that would create a dangerous elevation in blood pressure and therefore
should be avoided (McCabe, 1986)




